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Neurodegen 04

Topic: Pathology

Created on Monday, February 16 2009 by gliageek

Last modified on Monday, February 16 2009.


Courtesy of Dr. Mark Cohen
These anterior horn cells from this 63 year old who died with ALS contain which of the following proteins?

 
        A) TAR-DNA binding protein 43
 
        B) Lou Gherin
 
        C) Huntingtin
 
        D) Alpha-synuclein
 
        E) Paired helical filament Tau protein
 

 


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This question was created on February 16, 2009 by gliageek.
This question was last modified on February 16, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) TAR-DNA binding protein 43

This answer is correct.


The major component of intraneuronal inclusions in familial and sporadic ALS   (See References)

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B) Lou Gherin

This answer is incorrect.


Made it up   (See References)

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C) huntingtin

This answer is incorrect.


Huntington disease   (See References)

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D) alpha-synuclein

This answer is incorrect.


Multiple system atrophy   (See References)

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E) paired helical filament Tau protein

This answer is incorrect.


Tauopathies, chemotoxicity   (See References)

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References:

1. Love, S., Louis, D.N., and Ellison, D.W. (2008). Greenfield's Neuropathology, 8th Edition. Oxford University Press, USA (ISBN:0340906820) Advertising:
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pathology
Neurodegen 04
Question ID: 021609140
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/16/2009
Modified: 02/16/2009
Estimated Permutations: 120

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