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Myelin 10

Topic: Pathology

Created on Sunday, February 15 2009 by gliageek

Last modified on Thursday, April 9 2009.

Courtesy of Dr. Mark Cohen

This is an axial section of gross brain through the pons. The lesion shown in this image is associated with which of the following clinical scenarios?

A) Hypokalemia, corrected too rapidly

B) Hypernatremia, corrected too rapidly

C) Hyponatremia, corrected too rapidly

D) Hyponatremia, corrected too slowly

E) Hyperkalemia, corrected too slowly

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This question was created on February 15, 2009 by gliageek.
This question was last modified on April 09, 2009.

ANSWERS AND EXPLANATIONS

A) Hypokalemia, corrected too rapidly

This answer is incorrect.

The lesion shown in this image represents Central Pontine Myelinolysis (CPM). CPM is a demyelinating/necrotizing lesion felt to result from osmotic stresses produced from over-rapid correction of hyponatremia. (See References)


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B) Hypernatremia, corrected too rapidly

This answer is incorrect.


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C) Hyponatremia, corrected too rapidly

This answer is correct.


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D) Hyponatremia, corrected too slowly

This answer is incorrect.


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E) Hyperkalemia, corrected too slowly

This answer is incorrect.


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References:

1. Love, S., Louis, D.N., and Ellison, D.W. (2008). Greenfield's Neuropathology, 8th Edition. Oxford University Press, USA (ISBN:0340906820)

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pathology
Myelin 10
Question ID: 040909054
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/15/2009
Modified: 04/09/2009
Estimated Permutations: 4200