Migraine Treatments

Rescue Treatments for Acute Migraine

sumatriptan 6 mg subcutaneously
chlorpromazine 12.5 mg slow IV push q 20 min (maximum 50 mg)
prochlorperazine 10 mg slow IV push
droperidol 2.5 mg slow IV push q 30 min (maximum 7.5 mg)
depakon 1 gram IV push over 1 min
magnesium sulfate 1 gram IV push over 1 min

DHE45 + prochlorperazine
Mix DHE45 1 mg plus prochlorperazine 10 mg.
Give 1.5 ml slow IV push over 1-3 min.

dexamethasone 6-8 mg IV push
methylprednisolone 250-500 mg IV push
olanzapine 5-10 mg PO

Dr. Mikolaenko's cocktail:

Benadryl 25/50 IV

Reglan 10 mg

Lorazepam 1 mg IV

4 doses Q 6hrs