Neurocutaneous Syndromes 01

Topic: Adult

Created on Saturday, February 17 2007 by jdmiles

Last modified on Saturday, February 17 2007.

 
        A) Cafe au lait spots
 
        B) Poliosis
 
        C) Genetic abnormality on chromosome 22
 
        D) Shagreen patches
 
        E) Bilateral acoustic Schwannoma
 

 

	= Go back to the top of the page.
	= Reload a different version of this question ().
	= Load a random question from the database.
	= Use this question as a template to create a totally NEW question.
	= Enter detailed rating for this question!
	= How users like you have rated this question.

This question was created on February 17, 2007 by jdmiles.
This question was last modified on February 17, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

---

A) cafe au lait spots

This answer is correct.

The presence of 6 or more cafe au lait spots exceeding 1.5 cm in diameter (after puberty), is strongly associated with NF1.   (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

B) poliosis

This answer is incorrect.

Poliosis (presence of a small patch of white hair) is not characteristic of NF1. It is associated with tuberous sclerosis.   (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

C) genetic abnormality on chromosome 22

This answer is incorrect.

The genetic defect in NF1 is on chromosome 17. A defect on chromosome 22 is associated with neurofibromatosis type 2 (NF2).   (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

D) shagreen patches

This answer is incorrect.

Shagreen patches are not characteristic of NF1. They are associated with tuberous sclerosis.   (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

E) bilateral acoustic Schwannoma

This answer is incorrect.

Bilateral acoustic Schwannoma is associated with neurofibromatosis type 2 (NF2).   (See References)

Please log in if you want to rate questions.

 

 

 

 

References:

1. Neurofibromatosis Fact Sheet, NINDS. NIH Publication No. 06-2126
2. Victor, M., and Ropper, A.H. (2001). Adams and Victor's Principles of Neurology, 7th Edition. McGraw-Hill, New York. Pp. 1069-1076.
3. Santos, C.C., Miller, V.S., and Roach, E.S. (2004). Neurocutaneous syndromes. In Bradley, W.G., Daroff, R.B., Fenichel, G.M., and Jankovic, J. (Eds.). Neurology in Clinical Practice, 4th Edition. Butterworth Heinemann, Philadelphia. Pp. 1867-1900.

Please log in if you want to rate questions.

 

FrontalCortex.com -- Neurology Review Questions -- Neurology Boards -- Board Review -- Residency Inservice Training Exam -- RITE Exam Review
adult
Neurocutaneous Syndromes 01
Question ID: 021707087
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 02/17/2007
Modified: 02/17/2007
Estimated Permutations: 84000