GFAP staining - Example of pathological findings

Last updated on Saturday, April 4 2009 by jdmiles

GFAP staining - Example of pathological findings

This is a sample of glioblastoma multiforme (GBM). GBM is an astrocytoma, a type of tumor derived from or demonstrating features of astrocyte cell lines. This tissue has been stained using immunohistochemical staining for GFAP. Any brown in this image indicates the presence of GFAP, which is a marker specific for astrocytes, ependyma, or tumor cells derived from those cell types.

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GFAP staining - Example of pathological findings
This is an immunohistochemical stain. The presence of brown staining is indicative for glial fibrillary acidic protein (GFAP). GFAP is absent wherever there is no brown stain.