Multicystic Encephalopathy

Last updated on Tuesday, September 9 2008 by jdmiles

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Multicystic encephalopathy, whole mount, H&E stain
Cystic degeneration of all but molecular layer and regions of white matter

Multicystic Encephalopathy Brainstem
Bilateral cystic cavitation involving tegmental regions of brainstem

Multicystic Encephalopathy Coronal
Cystic degeneration involving both gray and white matter with some preservation of posterior circulation structures (inferior temporal lobes, bilaterally)

Multicystic Encephalopathy, horizontal section
Advanced cavitation of subcortical and deep white matter with relative preservation of cerebral cortical structures

Multicystic Encephalopathy In Situ
Bilateral collapse of intact cerebral surface secondary to advanced cystic degeneration of underlying white matter

Multicystic encephalopathy with status marmoratus
Prolonged survival after perinatal thalamic damage results in aberrant myelination of reactive astrocytic processes which manifests grossly as hypermyelination, termed status marmoratus (the marbled state).