Perinatal Disorders of Gray Matter

Last updated on Tuesday, September 9 2008 by jdmiles

Related images:

Acute hypotensive brainstem necrosis, hypoglossal nucleus, H&E stain
Eosinophilic neuronal degeneration involving tegmental brainstem nuclei

Hypotensive brainstem necrosis
Bilateral dusky discoloration of pontine tegmentum

Hypotensive Brainstem Necrosis
Bilateral dusky discoloration of medullary tegmentum

Intrauterine Infarct Coronal
Cystic cavitation of left middle cerebral artery distribution infarct in a newborn, consistent with prenatal occurrence

Neuronal mineralization, thalamic neurons, H&E stain
Perinatal ischemic neuronal necrosis may result in mineralization of degenerating thalamic neurons in the neonatal brain.

Hypotensive brainstem necrosis, organizing phase, H&E stain
Infarct with organization involving brainstem tegmental nuclei

Ulegyria, coronal section of brain, close-up
Cystically cavitated interposed gyrus and otherwise normal region of adult cerebral cortex, indicative of perinatal/neonatal time of infarction (secondary to high water content of immature brain)

Unilateral hemorrhagic necrosis involving right cerebral hemisphere, coronal section
Unilateral hemorrhagic necrosis in a stillborn infant, consistent with prenatal time of occurrence. Note also subependymal germinal matrix hemorrhage on left.