Guess the disease!
Topic: Behavior
Created on Wednesday, February 21 2007 by jdmiles
Last modified on Wednesday, February 21 2007.
GUESS WHAT I'M THINKING!
I'm thinking of a myelopathy related to infection with the HTLV-I virus. It is endemic to Martinique, Jamaica, Colombia and Japan. Key clinical signs include slowly progressing paraparesis with increased DTRs and positive Babinski.
What disease am I thinking of?
A) Wernicke's Encephalopathy B) Wilson's Disease C) Tropical Spastic Paraparesis D) Reye's Syndrome E) Sydenham Chorea
This question was created on February 21, 2007 by jdmiles.
This question was last modified on February 21, 2007.
ANSWERS AND EXPLANATIONS
A) Wernicke's Encephalopathy
This answer is incorrect.
Wernicke's Encephalopathy is a syndrome of ophthalmoparesis, nystagmus, ataxia, and confusion. Other findings often include postural hypotension and hypothermia. It is associated with thiamine deficiency, often secondary to malnutrition or alcoholism. (
See References)
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B) Wilson's Disease
This answer is incorrect.
Wilson's Disease is a disease wherein decreased cerluloplasmin leads to deposition of copper first in the liver and later in the brain (especially putamen and globus pallidus). Common symptoms include tremor and bradykinesia. Treatment is with d-penicillamine. (
See References)
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C) Tropical Spastic Paraparesis
This answer is correct.
Tropical Spastic Paraparesis is a myelopathy related to infection with the HTLV-I virus. It is endemic to Martinique, Jamaica, Colombia and Japan. Key clinical signs include slowly progressing paraparesis with increased DTRs and positive Babinski. (
See References)
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D) Reye's Syndrome
This answer is incorrect.
Reye's Syndrome is a form of hepatic encephalopathy, marked by fatty liver and cerebral edema. It is seen in children and adolescents, and is associated with the use of aspirin during viral infections, especially influenza and varicella. (
See References)
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E) Sydenham Chorea
This answer is incorrect.
Sydenham Chorea is a choreiform disorder associated with streptococcal infection. (
See References)
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References:
| 1. Victor, M., and Ropper, A.H. (2001). Adams and Victor's Principles of Neurology, 7th Edition. McGraw-Hill, New York. | |
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behavior
Guess the disease!
Question ID: 02210701
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 02/21/2007
Modified: 02/21/2007
Estimated Permutations: 0