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Pathology in Ischemic Stroke 03

Topic: Pathology

Created on Saturday, February 24 2007 by jdmiles

Last modified on Saturday, February 24 2007.

A patient presents with an acute ischemic stroke and dies 6 months later. Of the following choices, which is most likely to be seen on pathological examination of the brain at autopsy?

A) Appearance of reactive astrocytes at the edge of the infarct

B) Acute neuronal necrosis

C) Eosinophilic changes in neurons

D) Tissue pallor

E) Liquefaction necrosis

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This question was created on February 24, 2007 by jdmiles.
This question was last modified on February 24, 2007.

ANSWERS AND EXPLANATIONS

A) appearance of reactive astrocytes at the edge of the infarct

This answer is incorrect.

Appearance of macrophages, capillary proliferation, and the appearance of reactive astrocytes at the edge of the infarct occur 2 days to 2 weeks after the infarct. (See References)


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B) acute neuronal necrosis

This answer is incorrect.

Tissue pallor, acute neuronal necrosis, and eosinophilic changes in neurons are seen 12-24 hours after an acute ischemic stroke. (See References)


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C) eosinophilic changes in neurons

This answer is incorrect.

Tissue pallor, acute neuronal necrosis, and eosinophilic changes in neurons are seen 12-24 hours after an acute ischemic stroke. (See References)


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D) tissue pallor

This answer is incorrect.

Tissue pallor, acute neuronal necrosis, and eosinophilic changes in neurons are seen 12-24 hours after an acute ischemic stroke. (See References)


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E) liquefaction necrosis

This answer is correct.

Cavitation, liquefaction necrosis, and the formation of a glial scar at the edge of the infarct occur months to years after the infarct. (See References)


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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier, Philadelphia.


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pathology
Pathology in Ischemic Stroke 03
Question ID: 022407197
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 02/24/2007
Modified: 02/24/2007
Estimated Permutations: 5400