GQ1B Antibodies

Topic: Adult

Created on Sunday, October 5 2008 by jdmiles

Last modified on Sunday, October 5 2008.

 
        A) A syndrome of optic neuritis and transverse myelitis
 
        B) Myasthenia gravis
 
        C) Devic disease
 
        D) Miller-Fisher Syndrome
 
        E) Being eaten by a bear
 

 

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This question was created on October 05, 2008 by jdmiles.
This question was last modified on October 05, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

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A) A syndrome of optic neuritis and transverse myelitis

This answer is incorrect.

Neuromyelitis (also called Devic disease) is a demyelinating disease in which the attacks are limited to transverse myelitis and optic neuritis. It is not associated with antibodies to GQ1b ganglioside.  (See References)

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B) Myasthenia gravis

This answer is incorrect.

Myasthenia gravis is not associated with antibodies to GQ1b ganglioside.  (See References)

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C) Devic disease

This answer is incorrect.

Neuromyelitis optica (also called Devic disease or NMO) is a demyelinating disease in which the attacks are limited to transverse myelitis and optic neuritis. It is not associated with antibodies to GQ1b ganglioside.  (See References)

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D) Miller-Fisher Syndrome

This answer is correct.

The presence of GQ1B antibodies is associated with the Miller-Fisher syndrome (MFS). MFS is a variant of Guillain-Barre syndrome. Patients with MFS have minimal weakness, and usually a good prognosis. The defining features of MFS are ataxia, ophthalmoparesis, and arreflexia. Patients with MFS frequently have a positive titer for antibodies against GQ1b ganglioside.  (See References)

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E) Being eaten by a bear

This answer is incorrect.

Being eaten by a bear is not associated with antibodies to GQ1b ganglioside.
  (See References)

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References:

1. Allan H. Ropper, Robert H. Brown. . New York : McGraw-Hill Medical Pub. Division, 2005. (ISBN:007141620X)	Advertising:
2. Floyd, T. (1999). "Bear-inflicted human injury and fatality." Wilderness Environ Med, 10(2) 75-87. (PMID:10442155)

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adult
GQ1B Antibodies
Question ID: 100508132
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 10/05/2008
Modified: 10/05/2008
Estimated Permutations: 3600