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Adverse effects of AEDs 01

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

Which of the following is a hallmark side effect of phenytoin?

 
        A) Hirsutism
 
        B) Irritability
 
        C) Weight loss
 
        D) Hiccups
 
        E) Dupytren's contractures
 

 


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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) hirsutism

This answer is correct.


Side effects of phenytoin include gum hyperplasia, coarsening of the facies, hirsutism, and peripheral neuropathy.  (See References)

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B) irritability

This answer is incorrect.


Irritability is a hallmark side effect of vigabatrin, but is less characteristic of phenytoin.  (See References)

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C) weight loss

This answer is incorrect.


Weight loss is a hallmark side effect of topiramate and felbamate, but is less characteristic of phenytoin.  (See References)

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D) hiccups

This answer is incorrect.


Hiccups is a hallmark side effect of ethosuximide, but is less characteristic of phenytoin.  (See References)

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E) Dupytren's contractures

This answer is incorrect.


Dupytren's contractures is a hallmark side effect of barbiturates, but is less characteristic of phenytoin.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)
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pharmacology
Adverse effects of AEDs 01
Question ID: 12080701
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 11400480

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