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Adverse effects of AEDs 10

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

Which of the following is a hallmark side effect of topiramate?

 
        A) Weight gain
 
        B) Aplastic anemia
 
        C) Hyponatremia
 
        D) Pancreatitis
 
        E) Paresthesias
 

 


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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) weight gain

This answer is incorrect.


Weight gain is a hallmark side effect of gabapentin and valproate, but is less characteristic of topiramate.  (See References)

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B) aplastic anemia

This answer is incorrect.


Aplastic anemia is a hallmark side effect of felbamate, but is less characteristic of topiramate.  (See References)

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C) hyponatremia

This answer is incorrect.


Hyponatremia is a hallmark side effect of oxcarbazepine and carbamazepine, but is less characteristic of topiramate.  (See References)

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D) pancreatitis

This answer is incorrect.


Pancreatitis is a hallmark side effect of valproate, but is less characteristic of topiramate.  (See References)

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E) paresthesias

This answer is correct.


Side effects of topiramate include weight loss, paresthesias, impaired cognition, anorexia, and renal calculi.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)
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pharmacology
Adverse effects of AEDs 10
Question ID: 12080710
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 12285000

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