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Neurodegen 02

Topic: Anatomy

Created on Sunday, February 8 2009 by gliageek

Last modified on Sunday, February 8 2009.


Courtesy of Dr. Mark Cohen

This pattern of spinal cord damage is most consistent with which of the following diseases?

 
        A) Ataxia-telangiectasia
 
        B) Subacute combined degeneration
 
        C) Tabes dorsalis
 
        D) ALS
 
        E) Fredreich ataxia
 

 


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This question was created on February 08, 2009 by gliageek.
This question was last modified on February 08, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Ataxia-telangiectasia

This answer is incorrect.


Spinal cord degeneration generally restricted to posterior columns, especially gracile tracts  (See References)

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B) Subacute combined degeneration

This answer is incorrect.


Though there is variability, the posterior columns and corticospinal tracts are usually most severely affected  (See References)

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C) Tabes dorsalis

This answer is incorrect.


Spinocerebellar tracts are generally spared in Tabes dorsalis  (See References)

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D) ALS

This answer is incorrect.


ALS would show corticospinal degeneration, both laterally and anteriorly  (See References)

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E) Fredreich ataxia

This answer is correct.


Combined spinocerebellar and posterior column degeneration is characteristic of Fredreich ataxia  (See References)

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References:

1. Graham, D.I., and Lantos, P.L. (2002). Greenfield's Neuropathology, 7th ed. Arnold Press, New York. (ISBN:0340742313)Advertising:
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anatomy
Neurodegen 02
Question ID: 020809081
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/08/2009
Modified: 02/08/2009
Estimated Permutations: 120

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