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Neuromuscular 05

Topic: Pathology

Created on Saturday, February 14 2009 by gliageek

Last modified on Saturday, February 21 2009.


Courtesy of Dr. Mark Cohen
The histopathologic features seen within this trichrome stained muscle biopsy may be seen in all of the following conditions, EXCEPT:

 
        A) Post-polio syndrome
 
        B) Myofibrillary myopathy
 
        C) Cochicine myopathy
 
        D) Oculopharyngeal dystrophy
 
        E) Inclusion body myositis
 

 


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This question was created on February 14, 2009 by gliageek.
This question was last modified on February 21, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Post-polio syndrome

This answer is incorrect.


Rimmed vacuoles have been reported in post-polio syndrome, and may be seen in chronic denervation   (See References)

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B) Myofibrillary myopathy

This answer is incorrect.


Rimmed vacuoles are seen in some of the myofibrillary myopathies   (See References)

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C) Cochicine myopathy

This answer is correct.


Dilated lysosomes are not surrounded by granular material in colchicine myopathy   (See References)

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D) Oculopharyngeal dystrophy

This answer is incorrect.


Rimmed vacuoles are common in OPD   (See References)

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E) Inclusion body myositis

This answer is incorrect.


Rimmed vaculoles are one of the cardinal manifestations of IBM   (See References)

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References:

1. Graham, D.I., and Lantos, P.L. (2002). Greenfield's Neuropathology, 7th ed. Arnold Press, New York. (ISBN:0340742313) Advertising:
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pathology
Neuromuscular 05
Question ID: 021409122
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/14/2009
Modified: 02/21/2009
Estimated Permutations: 120

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