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Adverse effects of AEDs 10

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

Which of the following is a hallmark side effect of topiramate?

 
        A) Paresthesias
 
        B) Thrombocytopenia
 
        C) Hyponatremia
 
        D) Nervousness
 
        E) Hypersalivation
 

 


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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) paresthesias

This answer is correct.


Side effects of topiramate include anorexia, renal calculi, paresthesias, weight loss, and impaired cognition.  (See References)

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B) thrombocytopenia

This answer is incorrect.


Thrombocytopenia is a hallmark side effect of valproate, but is less characteristic of topiramate.  (See References)

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C) hyponatremia

This answer is incorrect.


Hyponatremia is a hallmark side effect of carbamazepine and oxcarbazepine, but is less characteristic of topiramate.  (See References)

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D) nervousness

This answer is incorrect.


Nervousness is a hallmark side effect of tiagabine, but is less characteristic of topiramate.  (See References)

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E) hypersalivation

This answer is incorrect.


Hypersalivation is a hallmark side effect of benzodiazepines, but is less characteristic of topiramate.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)
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pharmacology
Adverse effects of AEDs 10
Question ID: 12080710
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 12285000

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