Neurologic Sequellae of Nutritional Deficiencies 03

Topic: Imaging

Created on Wednesday, September 24 2008 by jdmiles

Last modified on Wednesday, September 24 2008.

 
        A) Vitamin B6
 
        B) Vitamin B1
 
        C) Vitamin B12
 
        D) Penicillamine-D
 
        E) Vitamin E
 

 

	= Go back to the top of the page.
	= Reload a different version of this question ().
	= Load a random question from the database.
	= Use this question as a template to create a totally NEW question.
	= Enter detailed rating for this question!
	= How users like you have rated this question.

This question was created on September 24, 2008 by jdmiles.
This question was last modified on September 24, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

---

A) vitamin B6

This answer is incorrect.

The patient's imaging and history are consistent with Wernicke encephalopathy. Vitamin B6 is not the definitive treatment for this disorder.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

B) vitamin B1

This answer is correct.

This FLAIR MRI shows hyperintensity in the medial thalamic nuclei, which is characteristic of Wernicke encephalopathy and Korsakoff dementia. The typical symptoms of Wernicke encephalopathy include ophthalmoparesis, nystagmus, ataxia, and a change in mental status characterized by confusion and apathy. Wernicke encephalopathy and Korsakoff dementia are both due to a deficiency of thiamine (vitamin B1), and both are more common in alcoholics. Treatment of Wernicke encephalopathy requires administration of thiamine. Adams and Victor recommend 50mg IV and 50mg IM immediately, followed by 50mg IM daily.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

C) vitamin B12

This answer is incorrect.

The patient's imaging and history are consistent with Wernicke encephalopathy. Vitamin B12 is not the definitive treatment for this disorder.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

D) penicillamine-D

This answer is incorrect.

The patient's imaging and history are consistent with Wernicke encephalopathy. Penicillamine-D is a chelating agent used in the treatment of Wilson's disease.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

E) vitamin E

This answer is incorrect.

The patient's imaging and history are consistent with Wernicke encephalopathy. Vitamin E is not the definitive treatment for this disorder.  (See References)

Please log in if you want to rate questions.

 

 

 

 

References:

1. Victor, M., and Ropper, A.H. (2001). Adams and Victor's Principles of Neurology, 7th Edition. McGraw-Hill, New York.
2. Rowland, L.P. (Ed) (2000). Merritt's Neurology, 10th Edition. Lippincott Williams & Wilkins, Philadelphia.
3. So, Y.T., and Simon, R.P. (2004). Deficiency diseases of the nervous system. In Bradley, W.G., Daroff, R.B., Fenichel, G.M., and Jankovic, J. (Eds.). Neurology in Clinical Practice, Fourth Edition. Butterworth Heinemann, Philadelphia, pp. 1693-1708.
4. Koguchi, K., Nakatsuji, Y., Abe, K., and Sakoda, S. (2004). "Wernicke's encephalopathy after glucose infusion." Neurology, 62(3) 512. (PMID:14872047)

Please log in if you want to rate questions.

 

FrontalCortex.com -- Neurology Review Questions -- Neurology Boards -- Board Review -- Residency Inservice Training Exam -- RITE Exam Review
imaging
Neurologic Sequellae of Nutritional Deficiencies 03
Question ID: 092408140
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 09/24/2008
Modified: 09/24/2008
Estimated Permutations: 30240