Adverse effects of AEDs 07

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

 
        A) Dupytren's contractures
 
        B) Insomnia
 
        C) Hepatoxicity
 
        D) Weight gain
 
        E) Emotional changes
 

 

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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

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A) Dupytren's contractures

This answer is incorrect.

Dupytren's contractures is a hallmark side effect of barbiturates, but is less characteristic of valproate.  (See References)

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B) insomnia

This answer is incorrect.

Insomnia is a hallmark side effect of felbamate and vigabatrin, but is less characteristic of valproate.  (See References)

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C) hepatoxicity

This answer is incorrect.

Hepatoxicity is a hallmark side effect of felbamate, but is less characteristic of valproate.  (See References)

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D) weight gain

This answer is correct.

Side effects of valproate include pancreatitis, thrombocytopenia, tremor, hair loss, hyperammonemia, hepatotoxicity, and weight gain.  (See References)

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E) emotional changes

This answer is incorrect.

Emotional changes is a hallmark side effect of tiagabine, but is less characteristic of valproate.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)

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pharmacology
Adverse effects of AEDs 07
Question ID: 12080707
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 12558000