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Basic Neuropathology 02

Topic: Pathology

Created on Tuesday, November 27 2007 by jdmiles

Last modified on Tuesday, November 27 2007.

Which of the following statements is most accurate regarding the space indicated by the unnecessarily large red arrow in the image above?


 
        A) This is an artifact created during sectioning
 
        B) This space is edema surrounding the big tumor in the middle of it
 
        C) This is a Virchow-Robin space
 
        D) This is a pocket of gas created by bacteria post-mortem
 
        E) This space is symptomatic of increased intracranial pressure
 

 


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This question was created on November 27, 2007 by jdmiles.
This question was last modified on November 27, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) This is an artifact created during sectioning

This answer is incorrect.


This is not an artifact.  (See References)

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B) This space is edema surrounding the big tumor in the middle of it

This answer is incorrect.


The unnecessarily large red arrow is pointing to a Virchow-Robin space. Virchow-Robin spaces are normal spaces, sometimes visible on MRI, which are lined with pia and are extensions of the subarachnoid space. These spaces continue along arteries, but are not found around capillaries.  (See References)

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C) This is a Virchow-Robin space

This answer is correct.


The unnecessarily large red arrow is pointing to a Virchow-Robin space. Virchow-Robin spaces are normal spaces, sometimes visible on MRI, which are lined with pia and are extensions of the subarachnoid space. These spaces continue along arteries, but are not found around capillaries.  (See References)

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D) This is a pocket of gas created by bacteria post-mortem

This answer is incorrect.


Pockets of gas, created by bacteria if the body remains unfixed for too long post-mortem, do sometimes occur. This creates the artifact called "swiss cheese brain."

However, this space is a normal space, not an artifact.

  (See References)

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E) This space is symptomatic of increased intracranial pressure

This answer is incorrect.


The unnecessarily large red arrow is pointing to a Virchow-Robin space. Virchow-Robin spaces are normal spaces, sometimes visible on MRI, which are lined with pia and are extensions of the subarachnoid space. These spaces continue along arteries, but are not found around capillaries.  (See References)

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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier Churchill Livingstone, Philadelphia. (ISBN:0443066582)Advertising:
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pathology
Basic Neuropathology 02
Question ID: 112707046
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 11/27/2007
Modified: 11/27/2007
Estimated Permutations: 42000

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