Agents that Affect Cholinergic Synapses - Super Quiz 01

Topic: Pharmacology

Created on Saturday, October 18 2008 by jdmiles

Last modified on Saturday, October 18 2008.

 
        A) Vesamicol inhibits acetylcholine uptake in presynaptic vesicles
 
        B) Beta-bungarotoxin decreases synthesis of acetylcholine
 
        C) Botulinum toxin irreversibly inhibits acetylcholinesterase
 
        D) Pilocarpine is a selective muscarinic receptor antagonist
 
        E) Tubocurarine is a selective muscarinic receptor antagonist
 

 

	= Go back to the top of the page.
	= Reload a different version of this question ().
	= Load a random question from the database.
	= Use this question as a template to create a totally NEW question.
	= Enter detailed rating for this question!
	= How users like you have rated this question.

This question was created on October 18, 2008 by jdmiles.
This question was last modified on October 18, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

---

A) vesamicol inhibits acetylcholine uptake in presynaptic vesicles

This answer is correct.

Vesamicol inhibits acetylcholine uptake in presynaptic vesicles  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

B) Beta-bungarotoxin decreases synthesis of acetylcholine

This answer is incorrect.

Beta-bungarotoxin causes spontaneous release of neurotransmitter from the presynaptic neuron  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

C) botulinum toxin irreversibly inhibits acetylcholinesterase

This answer is incorrect.

Botulinum toxin inhibits acetylcholine release from vesicles  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

D) pilocarpine is a selective muscarinic receptor antagonist

This answer is incorrect.

Pilocarpine is a muscarinic receptor agonist  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

E) tubocurarine is a selective muscarinic receptor antagonist

This answer is incorrect.

Tubocurarine is a nicotinic receptor antagonist  (See References)

Please log in if you want to rate questions.

 

 

 

 

References:

1. Zygmunt L. Kruk and Christopher J. Pycock. . London ; Chapman and Hall, 1991. (ISBN:412361108)	Advertising:
2. Gorio, A., Hurlbut, W.P., and Ceccarelli, B. (1978). "Acetylcholine compartments in mouse diaphragm. Comparison of the effects of black widow spider venom, electrical stimulation, and high concentrations of potassium." J Cell Biol, 78(3) 716-33. (PMID:701357)
3. Salin-Pascual, R.J., and Jimenez-Anguiano, A. (1995). "Vesamicol, an acetylcholine uptake blocker in presynaptic vesicles, suppresses rapid eye movement (REM) sleep in the rat." Psychopharmacology (Berl), 121(4) 485-7. (PMID:8619013)
4. McCann, C.M., Bracamontes, J., Steinbach, J.H., and Sanes, J.R. (2006). "The cholinergic antagonist alpha-bungarotoxin also binds and blocks a subset of GABA receptors." Proc Natl Acad Sci U S A, 103(13) 5149-54. (PMID:16549768)
5. Prasarnpun, S., Walsh, J., and Harris, J.B. (2004). "Beta-bungarotoxin-induced depletion of synaptic vesicles at the mammalian neuromuscular junction." Neuropharmacology, 47(2) 304-14. (PMID:15223309)

Please log in if you want to rate questions.

 

FrontalCortex.com -- Neurology Review Questions -- Neurology Boards -- Board Review -- Residency Inservice Training Exam -- RITE Exam Review
pharmacology
Agents that Affect Cholinergic Synapses - Super Quiz 01
Question ID: 10180801
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 10/18/2008
Modified: 10/18/2008
Estimated Permutations: 41038176000